Before Yotsuba, there is Azumanga Daioh. The manga and the extremely populer anime version ended in 2002, but still there are a large number of azumanga fans these day, especialy because of Osaka character (who could not be categorised as "cute", "sexy", or "spunky"). There are new Azumanga manga chapter, memoring its 10th anniversary, you can check at mangafox. The wallpaper size is 1280x1024, all credits go to hellknight @ deviantart.
